Regeneration of bone marrow after 5-FU treatment in WT and CXCR3 KO mice. WT and CXCR3 KO mice were treated with 225 mg/kg 5-FU on day 0. On days 0, 7, 9, and 11, BM (A) and CFU-GM (B) were analyzed for hematopoietic regeneration. KO mice demonstrated a significantly better BM recovery than WT mice. Each point represents the mean ± SEM in 2 independent experiments (n = 6; *P < .05).