The doubling time was not influenced by the interval of analysis. Among the patients with a rapid BCR-ABL1 rise, there was a significant difference in the measurement interval. However, when divided into groups according to the days over which BCR-ABL1 was measured, there was no difference between the doubling times (A). In contrast, there were significant differences in the fold rise (B), where a longer measurement interval led to a greater fold rise. *Significant differences between the groups (P ≤ .005, comparison between each group).