Meta-analyses for all studies in children with SCA that included full-scale IQ for those with and without SCIs. The meta-analyses include a total of 10 publications^7,86-94  comparing the mean difference in full-scale IQ between those children with SCA with and without SCIs. The x-axis reflects the mean full-scale IQ difference between those with and without an SCI. The horizontal lines represent the upper and lower boundaries of the 95% CI. If the 95% CI overlaps zero or crosses the zero threshold then no statistical differences were observed in that study. The black and gray diamonds represent the results of the fixed and random-effect models. The edges of the diamonds represent the 95% CI of the meta-analyses for the fixed and random-effect models. df, degree of freedom; MD, mean difference; SD, standard deviation. Adapted from King et al.²⁶