Figure 1
Figure 1. Genes differentially expressed between control and stably LMO2-transfected cell lines. (A) Three hundred eleven unique genes differentially expressed (5% FDR equivalent) between control cell lines, and cell lines that were stably transfected by LMO2. Shown are the log2 expression values, along with the mean change in expression between control and transfected lines. (B) Significant GO terms (P < .05) associated with genes shown in panel A. (C-D) Network analysis of genes regulated by LMO2 transfection. IPA was used to visualize significant networks of interactions between genes identified as differentially expressed in LMO2 stable transfection experiments. Corresponding to the GO enrichments (B), networks involved in cell cycle/proliferation (C), and inflammatory response/regulation of cell death (D) were significant by IPA analysis.

Genes differentially expressed between control and stably LMO2-transfected cell lines. (A) Three hundred eleven unique genes differentially expressed (5% FDR equivalent) between control cell lines, and cell lines that were stably transfected by LMO2. Shown are the log2 expression values, along with the mean change in expression between control and transfected lines. (B) Significant GO terms (P < .05) associated with genes shown in panel A. (C-D) Network analysis of genes regulated by LMO2 transfection. IPA was used to visualize significant networks of interactions between genes identified as differentially expressed in LMO2 stable transfection experiments. Corresponding to the GO enrichments (B), networks involved in cell cycle/proliferation (C), and inflammatory response/regulation of cell death (D) were significant by IPA analysis.

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