Distribution of disease subsets and associated genomic lesions among the 3 classes of chromosome 7 lesions. (Top) Distribution of LOH detected by SNP-A in the cohort, separated according to the nature of the lesion ([UPD(7q), del(7q), monosomy 7]. Patients have been grouped as follows: red, AML + high risk and intermediate-2 MDS; gray, low risk and intermediate-1 MDS; blue, hypocellular MDS; black, MDS/MPN; and green, Fanconi anemia and JMML. (Middle) Distribution of disease status in patients with 7 LOH separated according the nature of the lesion. (Bottom) Additional SNP-A–detected genomic lesions separated according the same criteria as stated herein. MDS indicates myelodysplastic syndrome; AML, acute myeloid leukemia; UPD, uniparental disomy; monosomy 7, deletion of whole chromosome 7; del(7q), partial deletion involving 7q; and MDS/MPN, myelodysplastic syndrome/myeloproliferative neoplasm.