Figure 2
Figure 2. Bmp9-KO mice have a normal vascularized retina. (A-B) Visualization of blood vessels by isolectin B4 (iB4) staining of WT and Bmp9-KO retinas at P6. (C) Bar graphs show the relative distance covered by the vascular plexus calculated as the ratio of the vascular radius over the retinal radius in percentage at P5 (n = 6), P6 (n = 7), P7 (n = 9), and P10 (n = 4) from 2 litters. (D) Number of branching points at the capillary plexus and at the front of migration of P6 pups (n = 3 in each group). (E-F) Pericyte coverage was visualized by NG2 immunostaining. Error bars show SEM. (A-B) Scale bar = 200 μm.

Bmp9-KO mice have a normal vascularized retina. (A-B) Visualization of blood vessels by isolectin B4 (iB4) staining of WT and Bmp9-KO retinas at P6. (C) Bar graphs show the relative distance covered by the vascular plexus calculated as the ratio of the vascular radius over the retinal radius in percentage at P5 (n = 6), P6 (n = 7), P7 (n = 9), and P10 (n = 4) from 2 litters. (D) Number of branching points at the capillary plexus and at the front of migration of P6 pups (n = 3 in each group). (E-F) Pericyte coverage was visualized by NG2 immunostaining. Error bars show SEM. (A-B) Scale bar = 200 μm.

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