Figure 1
Figure 1. Identification of kinetin riboside from screen of novel leukemia cell lines. (A-B) FACS staining of TEX cells for CD34, CD38, CD44, and CD123. (C) Schematic of primary growth screen of TEX and M9-ENL1 cells using Alamar Blue. (D) Structure of kinetin riboside verified by NMR. (E) Seven chemotherapeutics were evaluated on TEX cells. (F) Kinetin riboside inhibited cell growth in TEX cells at submicromolar concentrations, but was not as effective on Lin− CB cells (P < .001; F-distribution).

Identification of kinetin riboside from screen of novel leukemia cell lines. (A-B) FACS staining of TEX cells for CD34, CD38, CD44, and CD123. (C) Schematic of primary growth screen of TEX and M9-ENL1 cells using Alamar Blue. (D) Structure of kinetin riboside verified by NMR. (E) Seven chemotherapeutics were evaluated on TEX cells. (F) Kinetin riboside inhibited cell growth in TEX cells at submicromolar concentrations, but was not as effective on Lin CB cells (P < .001; F-distribution).

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