Correlations with anti-IgM–induced BIM phosphorylation in CLL cells. Correlations between maximum IgM-induced phosphorylation of (A) BIM_EL or (B) BIM_L and prognostic markers and stable/progressive disease. (C) Correlations in the M-CLL subset, between maximum anti-IgM–induced phosphorylation of BIM_EL and BIM_L and stable/progressive disease. Graphs all show individual data points as well as means (horizontal line). Statistically significant differences between groups according to the Mann-Whitney statistical test are boxed (P < .05).