Sequential CT scans of the thorax and response to granulocyte transfusions. CT scan before granulocyte transfusions showed nodules in the right upper lobe (Ai, solid arrow, 2 cm) and right middle lobe (Aii, dotted arrow, 3.5 cm). CT after 4 transfusions of granulocytes revealed a new right pleural effusion, new right lower and middle lobe consolidation, and left lower lobe airspace disease, and enlargement of existing nodules (Bi-ii). CT after 5 additional granulocyte transfusions showed marked improvement in lung consolidations, accompanied by clinical resolution of fever, tachypnea, and hypoxia (Ci-ii). The granulocyte (× 10¹⁰) and lymphocyte (× 10⁹) content of each of the 9 transfused granulocyte components (arrows) is shown in the boxes above the arrows, with the corresponding increment in ANC shown below the arrows (D). Mean granulocyte content was 6.9 × 10¹⁰ cells per product.