A single-chain variable fragment (scFv) recognizes the activated conformation of the b3 subunit of the αIIbβ3 platelet receptor. Upon binding to platelets the scFv induces an oxidative platelet fragmentation that reduces tumor metastasis.
A single-chain variable fragment (scFv) recognizes the activated conformation of the b3 subunit of the αIIbβ3 platelet receptor. Upon binding to platelets the scFv induces an oxidative platelet fragmentation that reduces tumor metastasis.
