The pathophysiologic relevance of the platelet GPIIIa49-66 epitope (GP49) on experimental lung metastases of B16 melanoma. Mice were treated as described in “Experimental lung metastasis assay.” At day 21, mice were killed. (A) Mean number of surface nodules per lung. (B) Mean volume of nodules per lung. (C) Induction of platelet count drop was determined at different time points. n = 8. *Values with significant differences. n.s. indicates no significant difference.