Analysis of histone modifications across the ∼ 11-kb ANK1E promoter region in K562 and HUVECs. (Top) Location of the ANK1E promoter (exon 1E) and ANK1E 5′HS and ANK1E 3′HS1/2 (indicated by arrows). (Middle) Broad ChIPSeq profiles for histone modifications in K562 cells. (Bottom) ENCODE ChIPSeq profiles for histone modifications in HUVECs. The hg19 coordinates of the 11-kb region are shown below the panel.