Plerixafor mobilizes CXCR4⁺ cells into the peripheral blood. Normal (A,C) and leukemic (B,D) mice were treated with a single dose of plerixafor, and WBC and CXCR4 expression in peripheral blood was measured over time. (A-B) Peripheral blood WBC count of normal and leukemic mice treated with plerixafor. (C-D) CXCR4 expression in peripheral blood of normal and leukemic mice treated with plerixafor.