Squamous cell carcinoma of the left posterior buccal vestibule in a 14-year-old girl that was 6 years after transplantation, with a prior history of severe mucosal cGVHD. (A) Ulcerated, exophytic, and indurated lesion of the vestibule that was treated with wide excision and chemoradiation therapy. (B) Localized recurrence that was evident within weeks of completion of therapy.