Metformin administration helps FA HSPCs maintain quiescence. (A) Representative flow cytometry profiles of the cell cycle analysis for KSL cells: placebo-treated Fancd2^+/+ KSL cells (i), MET-treated Fancd2^+/+ KSL cells (ii), placebo-treated Fancd2^−/− KSL cells (iii), and MET-treated Fancd2^−/− KSL cells (iv). The percentages on the profiles indicate the mean value for each group. (B) Statistical analysis of the cell cycle status. Data are poled results from 10 to 15 mice.