Alignment of gene mutations, karyotype information, and CMML category for 275 patients. (A) Each column represents 1 of the 275 analyzed samples. Analyses of 9 investigated genes, the karyotype, and CMML category-1 or -2 are depicted by colored bars. Red bar indicates mutated gene; dark gray bar, nonmutated gene; white bar, no data available; light-gray bar, normal karyotype; black bar, aberrant karyotype; gray bar, CMML-1; and anthracite bar, CMML-2. (B) Concomitant events of SRSF2 with other mutations are also shown as a bar chart. The gray part represents SRSF2wt, the red one SRSF2mut within the analyzed subcohorts. SRSF2mut frequencies and significances (P values) are denoted; numbers of mutated/analyzed cases of the subcohorts are given in parentheses below the bars..