Cardiovascular magnetic resonance T2* images showing the heart and liver from 3 different patients at the same echo time (10.68 ms). (A) Normal appearance with a bright myocardial and liver signal indicating that there is no significant cardiac or hepatic iron loading (myocardial T2* 29 ms, liver T2* 22 ms). (B) Dark myocardial signal indicating severe myocardial siderosis (heart T2* 6.2 ms) but no liver iron (liver T2* 18 ms). *The spleen also has high signal, suggesting that there is no significant splenic iron loading. (C) Normal myocardial signal (heart T2* 24 ms) but dark liver consistent with severe hepatic iron overload (liver T2* 1.8 ms). Images courtesy of Dr J. P. Carpenter (The Royal Brompton Hospital, London, United Kingdom).