Figure 3
Figure 3. Analysis of the premyelodysplastic hematopoietic compartment in RUNX1(41-214) animals. (A-F) Percentage of various hematopoietic populations analyzed on flow cytometry. Average and SD values of MigR1 (□; n = 4) and RUNX1(41-214) (■; n = 5) animals are shown. Animals were analyzed 4-6 months after transplantation. Percentage represents values within EGFP+/RUNX1(41-214) cells. (G) Representative flow cytometric analysis of the stem/progenitor cell compartment. Lin− indicates EGFP+/Lin−/IL7Rα−; c-Kit+, EGFP+/Lin−/IL7Rα−/c-Kit+/Sca-1−; and KSL, EGFP+/Lin−/IL7Rα−/c-Kit+/Sca-1+.

Analysis of the premyelodysplastic hematopoietic compartment in RUNX1(41-214) animals. (A-F) Percentage of various hematopoietic populations analyzed on flow cytometry. Average and SD values of MigR1 (□; n = 4) and RUNX1(41-214) (■; n = 5) animals are shown. Animals were analyzed 4-6 months after transplantation. Percentage represents values within EGFP+/RUNX1(41-214) cells. (G) Representative flow cytometric analysis of the stem/progenitor cell compartment. Lin indicates EGFP+/Lin/IL7Rα; c-Kit+, EGFP+/Lin/IL7Rα/c-Kit+/Sca-1; and KSL, EGFP+/Lin/IL7Rα/c-Kit+/Sca-1+.

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