Skewing to myelopoiesis in RUNX1(41-214) animals. Flow cytometric analysis of percentage of (A) myeloid (CD11b or Gr-1) and (B) lymphoid (CD3 or B220) populations in peripheral blood of MigR1 (○) or RUNX1(41-214) (●) animals. Dashed lines connect average values for MigR1 animals, and solid lines connect average values of RUNX1(41-214) animals. *P < .05. BMT indicates bone marrow transplantation. Flow cytometric analysis of (C) myeloid progenitors, (D) common lymphoid progenitors, and (E) CD3- or B220-expressing cells in bone marrow of MigR1 (□) or RUNX1(41-214) (■) animals. Values represent average and SD within EGFP⁺ population. Experiments were performed 4-6 months after transplantation; n = 3 animals were used for each group. CMP, indicates common myeloid progenitor; GMP, granulocyte-macrophage progenitor; MEP, megakaryocyte-erythrocyte progenitor; and CLP, common lymphoid progenitor.