Detection of Myc expression and Myc translocations on DLBCL tumors from patients participating in N0489 ER-CHOP protocol for untreated DLBCL. (A) Expression of Myc by IHC in DLBCL tumors. (B) Representative cases of MYC IHC staining (original magnification ×400). (C) IHC staining of both Myc and pSTAT3 in DLBCL tumors (n = 23). (D) Myc translocations in DLBCL tumors by FISH (n = 29). (E) Comparison of Myc IHC and Myc FISH in DLBCL tumors (n = 24).