Loss of peripheral NK cells in SHIP−/− mice. (A) Percentages of the indicated organs containing NK cell (NK1.1+CD3− in the lymphocyte gate) populations in the indicated organs from SHIP+/+ (white circles), SHIP+/− (gray circles), and SHIP−/− (black circles) mice. Data are pooled from at least 8 independent experiments, and each dot represents data obtained from 1 mouse; horizontal lines indicate the mean. (B) Total NK cell numbers of the indicated organs. Data are pooled from at least 3 independent experiments, and each dot represents data obtained from one mouse; horizontal lines indicate the mean.