ADAMTS13 deficiency promotes myocyte apoptosis, whereas VWF-deficiency prevents it. (A) Representative photomicrographs stained for apoptotic myocytes using the TUNEL method and counterstained with hematoxylin from 1 mouse of each genotype. TUNEL positive cells are stained red and indicated by black arrows. (B) Quantification of TUNEL-positive cells in the infarcted region. Each dot is a mean of 16 fields from 4 serial sections (separated by 30 μm) per mouse. Horizontal bars indicate mean values. NS indicates nonsignificant.