Effect of TF inhibition on MPO and chemokine expressions in BERKBM mice. Tissue levels of MPO (A), MCP-1 (B), and KC (C) were analyzed in WTBM (open bar) or BERKBM (filled bar) mice injected with either a rat anti–mouse TF (n = 5 for WTBM; n = 14 for BERKBM) or control rat IgG antibodies (n = 8 for WTBM; n = 14 for BERKBM). Asterisks directly above the bars indicate statistically significant difference compared with WTBM controls within the same treatment: *P < .05; **P < .01; and ***P < .001.