Kaplan-Meier plot of time to relapse in patients achieving initial, partial, or complete response. Relapse was defined as a drop in platelet count to ≤50 × 109/L following a complete response (platelet count ≥100 × 109/L), partial response (platelet count ≥50 × 109/L), or initial response (increase in platelet counts of at least 30 × 109/L, platelet counts >50 × 109/L on day 10 and no clinical bleeding). No. at risk indicates number of patients with sustained complete or partial response. P = .03.