Extent of patient-donor SNP mismatching. The percent of pairs mismatched at each SNP position is shown for transplant pairs mismatched at (A) HLA-A,(B) HLA-B, (C) HLA-C, (D) HLA-DRB1, (E) HLA-DQB1, and (F) HLA-matched transplant pairs.¹¹  Of the 1078 SNPs common to both the HLA-mismatched and the HLA-matched population, there was a higher rate of patient-donor mismatching among HLA-mismatched pairs for 96% of the 1078 SNPs compared with the HLA-matched pairs. The difference between the percent of HLA-mismatched pairs and the percent of HLA-matched pairs¹¹  who were mismatched at each of 1078 SNP positions is graphically represented for (G) HLA-A, (H) HLA-B, (I) HLA-C, (J) HLA-DRB1, and (K) HLA-DQB1 mismatched pairs in this study. Percentiles >0 indicate a higher percent of HLA-mismatched transplants were mismatched at the SNP compared with HLA-matched pairs. Zero percentiles indicate the same percent of HLA-matched and -mismatched pairs were mismatched at the SNP position.