Impact of total number of unfavorable SNP genotypes on transplant outcome. The impact of the total number of unfavorable SNP genotypes was determined for patients and donors with complete SNP genotyping for all SNPs descriptive of the end point of interest. (A) Effect of unfavorable genotypes at SNPs rs209130, rs2075800, and rs394657 on grades III-IV acute GVHD. (B) Effect of unfavorable genotypes at SNPs rs2523957, rs3830076, rs2071479, and rs107822 on chronic GVHD. (C) Effect of unfavorable genotypes at SNPs rs2244546 and rs986522 on relapse. (D) Effect of unfavorable genotypes at SNPs rs915654 and rs429916 on transplant-related mortality. (E) Effect of 12 unfavorable SNP genotypes on survival.