The proportion of mDCs in sLNs of day 12 rap^Δ/Δ mice is elevated. FACS analysis of epidermis (A), dermis (B), and sLNs (C-D) of day 12 rap^fl/fl and rap^Δ/Δ littermates. Cells are gated on CD45⁺ (A), CD45⁺ MHC-II⁺ CD11c⁺ (B), lymphocytes (C), or MHC-II^high CD11c^int mDC (D). Numbers and bar graphs indicate mean frequency ± SEM of cells in the respective gate or quadrant (N = 5 mice for rap^fl/fl and N = 3 mice for rap^Δ/Δ).