Figure 1
![Figure 1. Platelets increase carotid ligation–induced VSMC inflammation in mice. (A) Platelets are activated after carotid ligation. The left carotid artery was permanently ligated, and the mice were treated with platelet-depleting antibody or control IgG. Plasma PF4 was measured by ELISA (n = 5 ±SD; *P < .01 vs 0). (B) Platelets promote inflammation in carotid ligation model. Plasma IL-6 was measured by ELISA in control and platelet-depleted mice after carotid ligation (n = 5 ± standard deviation [SD]; *P < .01 vs 0).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/121/21/10.1182_blood-2012-09-454710/4/4417f1.jpeg?Expires=1736046799&Signature=1-w~l6GawC8Jdy0O3d1ZTIVoA-h2UrseBeR77RQeD0gKs4uZDCikKjqGTGMWiPs-wyWmGpi0s84ooipHCo5dXreMJo0MeeP7BcO4Z2mocBqmtTVCatuEWj0jJ63MEuy4LJZhUpCDlj~4jBYeIdl-PngcM3RVYGn0HC4P386TIGrVWKt0jwbT9MmCUgqfSOGXD03RMarHHLL8QTcdli6Bvzw-9XQiIGABN32VnmxeL7HTv-iZ~PelJJ5UlOE~gq~wKVIy3tEKafdHxSyZGXePfEcbIeHN4eig8eIiHvHBhko7YlGsucyvuMwboUivsl~TSL5~JB0Hg4gmetdwX8umvw__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Platelets increase carotid ligation–induced VSMC inflammation in mice. (A) Platelets are activated after carotid ligation. The left carotid artery was permanently ligated, and the mice were treated with platelet-depleting antibody or control IgG. Plasma PF4 was measured by ELISA (n = 5 ±SD; *P < .01 vs 0). (B) Platelets promote inflammation in carotid ligation model. Plasma IL-6 was measured by ELISA in control and platelet-depleted mice after carotid ligation (n = 5 ± standard deviation [SD]; *P < .01 vs 0).
