DNA methylation profiles at EC-enriched gene promoters. Promoter DNA methylation profiles of (A) NOS3/eNOS and (B) CDH5/VE-Cadherin genes in HUVECs, AoSMCs, and hepatocytes. Levels of methylation are color coded, where blue represents unmethylation, purple represents partial methylation, and orange represents full methylation, as identified by the Illumina Infinium Human Methylation 450K Bead Array platform. Regions of repetitive elements are indicated in black, identified by the RepeatMasker program. Signal enrichment of Pol2 chromatin immunoprecipitation-seq data in HUVECs is shown in orange, with the maximum signal indicated on the y-axis. Black arrow denotes the TSS. The UCSC Genome Browser was used to generate the track displays.⁴⁶