Association of SNPs in the BMI1-PIP4K2A locus with B-ALL among Hispanic children, by ploidy. Association of 131 directly genotyped SNPs (black) and 1371 imputed SNPs (gray) with the risk for B-ALL, adjusted for sex, age, and the first 5 principal components. Circles denote associations for children with B-ALL compared with control children. Squares denote associations for children with nonhyperdiploid B-ALL compared with control children. Triangles denote associations for children with hyperdiploid B-ALL compared with control children.