FeCl3-induced injury of the carotid artery in control mice and mice with reduced platelet count. (A) Carotid arteries were topically injured with filter paper saturated with 10% FeCl3 for 90 seconds, and then time to occlusion was determined by an ultrasonic flow probe. The horizontal line indicates the mean time to occlusion. Each symbol represents one animal (n.s., not significant; *P < .05; **P < .01; ***P < .001). (B) Representative blood flow measurements are shown.