Figure 3
Figure 3. CD34+CD43+CD45−/low cells expanded on overexpression of Sox17 developmentally place between ECs and pre-HPCs/HPCs. Gene-expression patterns of wild-type and Sox17-overexpressing cells obtained in microarray analyses were clustered using hierarchical clustering. The distance between 2 samples was defined with the Pearson correlation using total genes (A) or certain probes selected from the GO database (B-C). “Transcription factor” represents genes that are located in the nucleus and have at least 1 of the GO terms “regulation of transcription, DNA-dependent,” “transcription factor activity,” or “transcription factor complex” (B). “Hemopoiesis” represents genes that are annotated with the GO terms “hemopoiesis,” “vasculogenesis,” “erythrocyte differentiation,” “erythrocyte maturation,” and/or “erythrocyte development” (C). The color of each cell represents the value of correlation indicated on the right side of the matrix.

CD34+CD43+CD45−/low cells expanded on overexpression of Sox17 developmentally place between ECs and pre-HPCs/HPCs. Gene-expression patterns of wild-type and Sox17-overexpressing cells obtained in microarray analyses were clustered using hierarchical clustering. The distance between 2 samples was defined with the Pearson correlation using total genes (A) or certain probes selected from the GO database (B-C). “Transcription factor” represents genes that are located in the nucleus and have at least 1 of the GO terms “regulation of transcription, DNA-dependent,” “transcription factor activity,” or “transcription factor complex” (B). “Hemopoiesis” represents genes that are annotated with the GO terms “hemopoiesis,” “vasculogenesis,” “erythrocyte differentiation,” “erythrocyte maturation,” and/or “erythrocyte development” (C). The color of each cell represents the value of correlation indicated on the right side of the matrix.

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