Inactivation of Gas6 protect mice against venous thrombosis. (A) FeCl3-induced thrombosis in the IVC of WT and Gas6−/− mice. Representative hematoxylin and eosin staining of thrombi shows that WT mice develop larger thrombi than Gas6−/− mice (original magnification ×4). (B) Quantification of thrombus weight demonstrated that thrombi from Gas6−/− mice weigh significantly less than thrombi from WT mice (n = 7). ***P < .001.