ETS1 and FLI1 affect genes involved in GC reaction. (A) Real-time PCR validation of down-regulation of CXCR5 and NFKB1 observed by gene expression profiling after ETS1 silencing. Histogram graphs represent the average of 4 independent silencing experiments. All down-regulation had a P value < .05. (B) Real-time PCR validation of down-regulation of CXCR4, CXCR7, CDC25B, and WEE1 observed by gene expression profiling after FLI1 silencing. Histogram graphs represent the average of 4 independent silencing experiments. All down-regulation had a P value < .05.