Clustering of FHL patient samples in accordance with the disease phenotype. Patients with FHL type 2 (ha), patients with unknown genetic cause of FHL and relapse (hb), and patients with rapidly evolving form of FHL (hc) were distinguished by the hierarchical clustering of all samples. The blue and red boxes on the right side of the heat map display down- and up-regulated genes, which are clustered according to disease subtypes.