Adjusted mean differences of the SF-36 scale scores obtained in patients with or without acute or chronic GVHD and controls. (A) Physical health and (B) mental health. A score below line 0 means a worse outcome for HSCT. Note that connecting lines among SF-36 outcomes are plotted for descriptive purposes only. *Statistically significant after Bonferroni’s correction (adjusted α = 0.05/8 = 0.00625). Statistical significance refers to comparisons of SF-36 scores between transplanted patients and matched control subjects. ^†Mean differences between transplanted patients and matched control subjects adjusted for age, gender, education, marital status, and comorbidity. A negative sign indicates worse outcomes for transplanted patients. ^‡Exceeds minimally important difference (ie, 8 points for SF-36 scales and 2 points for PCS and MCS scales). ^§Statistically significant (α = 0.05).