Baseline risk factors predicting for further therapy. (A) Abnormal baseline DLCO (<75% predicted) increases risk. (B) High urine total protein (≥0.093 g per 24 hours) increases risk. (C) Lack of CR or VGPR increases risk. (D) Increasing bone lesions does not increase risk. This figure does not include 3 patients who had more than 3 lesions.