Visualization of recurrent deletions on 9q and UPD on 13q that were present at diagnosis (indicated as D) and/or relapse (indicated as R) by dCHIP. (A) Log2 ratios of 6 patients with del(9q) at the time of diagnosis. Patients #8, #13, and #47 maintained the same deletions at both time points, whereas in patients #4, #5, and #21, del(9q) was lost. Blue indicates deleted and red indicates gained chromosomal segments. (B) Cases with UPD13q at diagnosis and relapse (n = 3), at diagnosis only (n = 1), or at relapse only (n = 7). Mutation status is indicated below the corresponding FLT3-ITD mutation: ^−/− no mutation; ^−/+, heterozygous mutation; ^+/+ homozygous mutation. Blue indicates homozygous (= LOH) and yellow heterozygous regions of chromosome 13 as determined by SNP profiling.