Transplantation-free and overall survival. Transplantation-free survival (A) and overall survival (B) after IST with r-ATG and CSA compared with h-ATG and CSA. Second-line HSCT was considered as an event in the analysis of transplantation-free survival. HSCT was performed in 20 patients at a median of 258 days (range, 57-504) after IST in the r-ATG group and in 29 patients with a median of 625 days (range, 27-3718) after IST in the h-ATG group.