Expression of markers of memory and senescence in TH cells. (A) Representative flow plots and summary of expression of PD1 and CD57 demonstrates relative absence of these markers of immunosuppression/senescence in CHL-TH compared with RLN-TH. (B) Representative flow plots and (C) summary of T memory subsets demonstrate a relative absence of TEMRA cells and increased proportion of CM cells in CHL-TH compared with RLN-TH. (D) The major differences in subset distribution between CHL-TH and RLN-TH, with bars divided according to the median proportion of cells defined by each memory phenotype and error bars omitted for clarity. Those subsets for which there are significant differences between CHL and RLN and presented with error bars in panel C.
