Figure 1
![Figure 1. Example of follicular hyperplasia features in a patient. (A) At low power examination, the lymph node architecture is preserved with florid follicular hyperplasia. Large follicles show irregular borders, a prominent germinal center, and sometimes enlarged mantle zone (original magnification ×2.5). (B) Reactive germinal centers show a bcl2−/bcl6+/CD10+ immunostaining pattern (original magnification ×2.5). (C) The karyotype of lymphadenopathy after G-banding was as follows: 46,XY,add(1)(q41),der(14)t(1;14)(q24;q32)[8]/46XY[12]. Derivative chromosomes are marked by arrows. (D) Polymerase chain reaction heteroduplex analysis of incomplete Ig heavy chain (IGH) DH-JH rearrangement: detection of a slight homoduplex band (280 bp).](https://ash.silverchair-cdn.com/ash/content_public/journal/blood/122/17/10.1182_blood-2013-07-513879/4/3082f1.jpeg?Expires=1735832814&Signature=hsonPHAJAXfYSTivllTuN0CCUNOhOxYZ21fBlrYH-nnxZP8yiTuuXusjgH8ZyIEmQyu~FIyH-4dqe43nYV2WAc-1Mp8GF5LmSH8ZSvWIz5aSAsLPBzB9BIKaYGOPN46rXW0J-AW9~etoqO5BkRHejqg6V7DHX28aHpXYedNVljGqMtT5m1l4OzVeQH83oHD3UHuC0ci-uhUKLFr5Iys4c1SjSsNKCfNZ-JSrGWKbjzmMfAO5cfE74VZ9XmbJLl2BE4KqoOnUb31OM~ZNMvPJMt46UG08pVdsIm36K~34OthZ~QVDX7Io6Xpr0BYVcRUpYZ0TSB8homcqQrZhUtCNQQ__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Example of follicular hyperplasia features in a patient. (A) At low power examination, the lymph node architecture is preserved with florid follicular hyperplasia. Large follicles show irregular borders, a prominent germinal center, and sometimes enlarged mantle zone (original magnification ×2.5). (B) Reactive germinal centers show a bcl2−/bcl6+/CD10+ immunostaining pattern (original magnification ×2.5). (C) The karyotype of lymphadenopathy after G-banding was as follows: 46,XY,add(1)(q41),der(14)t(1;14)(q24;q32)[8]/46XY[12]. Derivative chromosomes are marked by arrows. (D) Polymerase chain reaction heteroduplex analysis of incomplete Ig heavy chain (IGH) DH-JH rearrangement: detection of a slight homoduplex band (280 bp).
