Prolonged bleeding and blood vessel occlusion time in kindlin-2^+/−mice. (A) Total blood loss upon tail tip clip resection as measured by released hemoglobin using Drabkin reagent (n = 10). (B) Tail bleeding time as estimated after tail tip resection (n = 10 mice per group). (C) The time needed to form an occlusive thrombus in the carotid artery was determined in 10 control and 12 kindlin-2^+/− mice after topical injury with FeCl₃. (D) Tail bleeding time and (E) total blood loss in WT recipients 6 weeks after bone marrow transplantation from WT or kindlin-2^+/− donors.