Figure 1
Treatment schema. Cycles 13 to 18 (maintenance) carfilzomib dosing modified to days 1, 2, 15, 16. In cohort 6/7, 20 mg/m2 was given on days 1 and 2 during cycle 1 and 27 mg/m2 was given thereafter. D, day; IV, intravenous; MPD, maximum planned dose; PO, orally.
