GEE estimates of the longitudinal trends of sexual function domains and total sexual function. (A) Total sexual function. (B) Sexual behavior/experience. (C) Sexual cognition/fantasy. (D) Orgasm. (E) Sexual arousal. (F) Drive/relationship. Men: dashed lines denote estimated function; ▪, observed mean. Women: solid lines denote estimated function; ●, observed mean. Vertical lines show 95% CIs of the GEE trends. *Significant (P < .05) difference from pre-HCT level.