ESL-1-deficiency is characterized by a myeloid expansion in the steady state. Hematologic characterization of WT, ESL-1^−/−, PSGL-1^−/−, and DKO mice. (A) Lymphocyte, neutrophil, and monocyte counts in the blood of WT and mutant mice. (B) Spleen-to-body-weight (BW) ratios in WT and mutant mice. There were 3 to 9 mice per group. Data are shown as mean ± SEM and was analyzed by the unpaired Student t test.