OS of patients with 8/8 matched donors (solid line), patients with single allele mismatched donors at loci HLA-A, -B, -C, or -DRB1 (dashed line), and single antigen mismatched donors at loci HLA-A, -B, -C, or -DRB1 (dotted line). HLA-DQB1 status was omitted from this analysis because multivariate modeling indicated a possible differential impact of HLA-DQB1 allele and antigen mismatches. Comparison single allele vs single antigen mismatch, P = .924; comparison 8/8 matched vs 7/8 matched log-rank, P < .001.