Acquisition of GATA1 mutations is accompanied by a wave of hypermethylation changes at distinct loci. (A) Heatmap representation of differentially methylated regions between Tri21 FL-MNC and DS-TMD blasts. Each row represents a genomic region, and each column represents a patient sample. (B) Venn diagram representation of the overlap between the Tr1 FL-MNC vs control FL-MNC DMRs and the Tri21 FL-MNC vs DS-TMD DMRs.