Brentuximab vedotin blocks proliferation of PEL cells. Human PEL cell lines BC-1 (A), BC-3 (B), UM-PEL-1c (C), and UM-PEL-3c (D) were treated with brentuximab vedotin (B.V.) at indicated doses for 0, 24, 48, and 72 hours. Proliferative response at each time point was measured by MTS assay. Results are shown as fold change of proliferation compared with time 0 hours. Experiments depicted in panels A-D were repeated thrice independently in triplicate. The representative data from one experiment are shown. Error bars correspond to standard error of mean in all graphs.