A summary of known translocations involving the 9p24.1 locus in PMBCL and 2 novel fusion transcripts. (A) Translocations involving CD274 are depicted in gray, whereas those that are involved or situated downstream from PDCD1LG2 are depicted in black. Dot size and adjoining line thickness qualitatively depict the number of cases involving those loci; the CIITA-PDCD1LG2 line represents 4 cases. Three of the 6 depicted translocations are novel, PDCD1LG2-IGHV7-81, CIITA-PDCD1LG2, and KIAA1432-CLDN14. (B) Sanger-validated fusion transcripts involving PDCD1LG2; all 7 exons of PDCD1LG2 are depicted in dark gray and are in scale to one another. Known and suspected protein coding regions are drawn with a greater exon width.