Reduced CD48 expression in AML patients. (A) The relative expression of CD48 in samples of normal bone marrow (BM) was compared with samples of AML patients that express PML-RARA or AML1-ETO. Data obtained from Amazonia! (http://amazonia.transcriptome.eu/). Black horizontal line represents the median value. (B) Expression of CD48 in the BM of patients that were treated in Hadassah Medical Center. Relative copy number of CD48 was determined by qRT-PCR. The expression of 1 of the normal bone marrow samples was arbitrarily defined as 1. The results were normalized to 3 housekeeping genes (HPRT, UBC, and SDHA). The black horizontal lines represent the median value. ***P < .001, Student t test.